个人基本信息：

成娟丽，女，中共党员，微生物学博士，教授，硕士生导师，国家自然科学基金通信评审专家，全国研究生和本科生教育评估监测专家，陕西省微生物学学会会员。

研究方向： 微生物生理生化

招生方向： 微生物学、遗传学、生物与医药

科研项目和学术成果

（1）主持的国家级科研项目

1. 国家自然科学基金地区科学基金项目，32560048，SamR调控铜绿假单胞菌SAM合成与分配驱动群体感应信号分子AHLs快速积累的底物供应机制研究，2026/01-2029/12, 33万元，在研，主持.

2. 国家自然科学基金地区科学基金项目，31860012，ABC转运器ZnuEFGH介导铜绿假单胞菌锌离子摄取的分子机制研究，2019/01-2022/12, 40万元，已结题，主持.

3. 国家自然科学基金青年科学基金项目，31200040，微生物来源的细菌烯脂酰ACP还原酶抑制剂的新型细胞筛选模型的建立与应用研究，2013/01-2015/12, 23万元，已结题，主持.

（2）代表性论论文

Jing Feng^#, Dandan Liu^#, Wei Xiao, Peijie Fu, Juanli Cheng*, Jinshui Lin*. Targeting Drug-Resistant Pseudomonas aeruginosa: Emerging Roles of Plant-Derived Bioactive Compounds. Bacteria. 2026, 5(2):35.

Dandan Liu^#, Wei Xiao^#, Wenwen Li, Shengli Li, Juanli Cheng* and Jinshui Lin*. Bacillus velezensis LW-66: A Broad-Spectrum Biocontrol Agent Against Apple Tree Canker and Other Plant Fungal Diseases. Microorganisms, 2026, 14(4):889.

Wei Xiao^#, Xin Ma^#, Dandan Liu, Shengli Li, Juanli Cheng* and Jinshui Lin*. Trojan Horses: Conjugating Siderophores and Antibiotics—A New Approach to Treating Pseudomonas aeruginosa Infection. Microorganisms, 2026, 14(4):891.

Wanqing Ning, Zhaoren Wang, Yicheng Wang, Guangping Liu, Jing Zeng, Yanfeng Wang, Renjun Mao, Duo Cao, Juanli Cheng*, and Jinshui Lin*. Berberine: A Natural pqs System Inhibitor in Pseudomonas aeruginosa for Foodborne Infection Control. Journal of Agricultural and Food Chemistry, 2026, 74(13):10977–10988.

Jing Zeng#, Xin Ma#, Yu Zheng, Dandan Liu, Wanqing Ning, Wei Xiao, Qian Mao, Zhenqing Bai, Renjun Mao, Juanli Cheng* and Jinshui Lin*. Traditional Chinese Medicine Monomer Bakuchiol Attenuates the Pathogenicity of Pseudomonas aeruginosa via Targeting PqsR. International Journal of Molecular Sciences, 2025, 26(1):243.

Xufei Zhu#, Wanqing Ning#, Wei Xiao, Zhaoren Wang, Shengli Li, Jinlong Zhang, Min Ren, Chengnan Xu, Bo Liu, Yanfeng Wang, Juanli Cheng* and Jinshui Lin*. Isolation and Identification of Burkholderia stagnalis YJ-2 from the Rhizosphere Soil of Woodsia ilvensis to Explore Its Potential as a Biocontrol Agent Against Plant Fungal Diseases. Microorganisms, 2025, 13(6):1289.

Shuaitao Wang#, Juanli Cheng#, Yanting Niu, Panxin Li, Xiangqian Zhang and Jinshui Lin*. Strategies for Zinc Uptake in Pseudomonas aeruginosa at the Host-Pathogen Interface. Frontiers in Microbiology, 2021, 12:741873.

Jinshui Lin* and Juanli Cheng. Quorum Sensing in Pseudomonas aeruginosa and Its Relationship to Biofilm Development. In: Introduction to Biofilm Engineering. vol. 1323: ACS Symposium Series Ch. 1, 1-16 (American Chemical Society, 2019) DOI: 10.1021/bk-2019-1323.ch001

Jinshui Lin*, Juanli Cheng, Yao Wang, Xihui Shen. The Pseudomonas Quinolone Signal (PQS): Not Just for Quorum Sensing Anymore. Frontiers in Cellular and Infection Microbiology, 2018, 8:230.

Jinshui Lin#, Weipeng Zhang#, Juanli Cheng, Xu Yang, Kaixiang Zhu, Yao Wang, Gehong Wei, Pei-Yuan Qian, Zhao-Qing Luo, Xihui Shen. A Pseudomonas T6SS effector recruits PQS-containing outer membrane vesicles for iron acquisition. Nature Communications, 2017, 8:14888.

Jinshui Lin#, Juanli Cheng#, Keqi Chen, Chenghao Guo, Weipeng Zhang, Xu Yang, Wei Ding, Li Ma, Yao Wang, Xihui Shen. The icmF3 locus is involved in multiple adaptation- and virulence-related characteristics in Pseudomonas aeruginosa PAO1. Frontiers in cellular and infection microbiology, 2015, 5:70.

Juanli Cheng#, Jincheng Ma#, Jinshui Lin, Zhen-Chuan Fan, John E. Cronan and Haihong Wang. Only one of the five Ralstonia solanacearum long-chain 3-ketoacyl-ACP synthase homologues functions in fatty acid synthesis. Applied and Environmental Microbiology, 2012, 78(5): 1563-1573.

Lei Zhu#, Juanli Cheng#, Biao Luo, Saixiang Feng, Jinshui Lin, Shengbin Wang, John E Cronan and Haihong Wang. Functions of the Clostridium acetobutylicium FabF and FabZ proteins in unsaturated fatty acid biosynthesis. BMC Microbiology, 2009, 9:119

（3）出版著作

林金水，成娟丽.微生物学（普通高等教育“十三五”规划教材），吉林大学出版社，2018.

成娟丽.微生物学新概论.延边大学出版社，2019.

（4）获得专利

成娟丽，林金水，王红，细菌烯脂酰ACP还原酶抑制剂的筛选方法，2016.04.06，中国，ZL201410051932.9

林金水，成娟丽，张向前，王延峰，贺晓龙，王贵锋，田野，张恒，源自枣树链霉菌属JL-1、其活性物及制备方法和应用，中国，CN201710991832.8

林金水，王贵锋，成娟丽，田野，张向前，王延峰，王晶瑶，杨雯，酸枣抗菌增敏活性成分及其制备方法和应用，中国，CN201810435099.6

林金水，王帅涛，张恒，牛艳婷，高倩倩，杨建社，成娟丽，张宁梅，朱旭飞，师瑜倩，艾亚楠，方波，一种铜绿假单胞菌工程菌的构建方法及应用，中国，CN201911395153.X

成娟丽，林金水，牛艳婷，司青坡，吴勉，一种微生物有机肥生产用发酵搅拌装置，2020.05.15，中国，ZL201920810414.9

成娟丽，林金水，张宁梅，朱旭飞，司青坡，一种微生物分隔培养板，中国，ZL201821409121.1

联系方式：E-mail：chengjl-1981@163.com ，微信号：cjl306459535